97% of all people who qualify for genetic testing never get tested. We strongly believe in cancer prevention. Whether you are coming in specifically to discuss genetic testing or you are being seen for another reason, every single patient who comes to New England Breast and Wellness undergoes a cancer risk screening and assessment at their first visit. If you require genetic testing in Boston, we are able to perform this the same day you are seen.

Up to 10% of all breast cancers are caused by gene mutations passed down from a parent, i.e., inherited gene mutation. If you have an inherited gene mutation, your lifetime risk of breast cancer increases by up to 50% or more, depending on the specific gene mutation. Mutations can occur in numerous genes, but BRCA1 and BRCA2 gene mutations are the most common sources of breast cancer. At New England Breast and Wellness, genetic testing in Boston allows your doctor to identify inherited gene mutations in specific genes. In the past, genetic testing only identified BRCA1 and BRCA2 gene mutations, but we run the largest expanded panel testing to evaluate over 70 gene mutations. People with a higher risk of inherited gene mutation should undergo genetic testing because it helps us curate a comprehensive breast cancer risk mitigation program.

Genetic Testing Recommendations

You should consider genetic testing if:

  • A family member of yours has high-risk inherited gene mutations related to breast cancer, such as the BRCA1/2 inherited gene mutations.
  • You have a personal or family history of breast cancer before the age of 46.
  • You have a personal history of triple-negative breast cancer diagnosed before 60 years of age.
  • A close family member of yours has been diagnosed with breast cancer, and you have a personal history of breast cancer before 50 years of age.
  • A close family member of yours has been diagnosed with breast cancer before 50 years of age and you have a personal history of breast cancer at any age.
  • You have a personal and family history (at least 2 close family members) of breast cancer diagnosed at any age.
  • A close family member of yours has been diagnosed with breast cancer before 45.
  • You have a personal or family history of metastatic prostate cancer, aggressive prostate cancer, pancreatic cancer, or ovarian cancer at any age.
  • You have a family history of male breast cancer.
  • You have been diagnosed with breast cancer, and the tumor has been tested to reveal BRCA1/2 or other gene mutations.
  • You have been diagnosed with metastatic breast cancer.
  • You have a personal history of bilateral breast cancer diagnosed before 65 years of age.
  • You’re of Ashkenazi Jewish heritage.
  • You have at least a 2.5% risk of having BRCA1/2 gene mutations based on risk assessment.

When is genetic testing not recommended?
If you are the only individual in the family with breast cancer — and it has occurred after 45 years of age — there’s a small chance that you carry the BRCA1/2 gene mutation. You can undergo genetic testing at any age, but it’s not generally recommended if you have a very small risk of genetic mutations. You should undergo genetic counseling to determine if you need genetic testing in Boston.

Genetic Counseling

We conduct comprehensive genetic counseling before determining if you need genetic testing for BRCA1/2 or other inherited gene mutations. Dr. Katherina Calvillo will discuss the potential benefits and risks of genetic testing with you. She will also perform a risk assessment to determine if you belong to any of the high-risk categories mentioned earlier. We provide all the information you need to make an informed and educated decision about undergoing genetic testing.

patient and daughter after genetic testing for cancer
woman who had genetic testing at new england breast and wellness

Genetic Testing Results

  • Benign or Likely Benign: This means the results are normal, and you don’t have gene mutations linked to an increased risk of breast cancer.
  • Pathogenic or Likely Pathogenic: This means you’ve tested positive for a gene mutation linked to an increased risk of breast cancer.
  • Variant of Uncertain Significance: This is an inconclusive result that needs further investigation, but it’s most probably negative.

Regardless of the results of your genetic testing, you may go through a wide range of emotions. Please remember that testing positive for certain genetic mutations doesn’t mean you have or will have breast cancer; it simply means you have a higher risk. If you’ve tested positive for gene mutations linked to breast cancer, we will work collaboratively to curate a risk mitigation program for you. Please discuss the results of your Genetic Testing in Boston with your doctor.

Genetic Testing in Wellesley, MA

New England Breast and Wellness is committed to providing personalized, intimate, and comprehensive care for breast cancer patients. Whether you’re at a high risk of inherited gene mutations or have been diagnosed with breast cancer, we provide comprehensive genetic counseling to help you make an informed decision. Dr. Calvillo individually curates patient care programs according to your specific requirements and oversees all treatments. You can rest assured that we’ll be with you through every step of your journey.

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